Investigation of the mechanisms responsible for aggressive neuroblastoma and its poor prognosis is critical to identify novel therapeutic targets and improve survival.Enhancer of Zeste Homolog 2 (EZH2) is known to play a key role in supporting the malignant phenotype in several cancer types and knockdown of EZH2 has been shown to decrease tumorigen
BackgroundMyasthenia gravis (MG) is the most common paraneoplastic syndromes of thymoma and closely related to thymus abnormalities.Timely detecting of the risk of MG would benefit clinical management and treatment decision for patients with thymoma.Herein, we developed a 3D Trike DenseNet deep learning (DL) model based on preoperative computed tom
Abstract Background Culicoides, also known as biting midges, carry pathogens which include Mansonella perstans.Mansonella perstans is a nematode parasite implicated in a number of disease outcomes.Even though a high prevalence of about 75% M.perstans infection has been recorded in some communities in the middle belt of Ghana, and a wide diversity o
Autophagy has been implicated in innate immune responses against various intracellular pathogens.Recent studies have reported that autophagy can be triggered by pathogen recognizing sensors, including Toll-like receptors and cyclic guanosine monophosphate-adenosine monophosphate synthase, to participate in innate immunity.In the present study, we e
Social enterprises (SEs) are a new concept, integrating corporate profitability and social purposes.SEs seek to realize sustainable social values, rather than short-term profits.It is therefore important to study the factors that affect the sustainable management Washing Up Bowl of SEs.Corporate social responsibility (CSR) is known to improve corpo